Attempting to read a scientific article for the first time may seem overwhelming and confusing. This guide details how to read a scientific article step-by-step. First, you should not approach a scientific article like a textbook— reading from beginning to end of the chapter or book without pause for reflection or criticism. Additionally, it is highly recommended that you highlight and take notes as you move through the article. Taking notes will keep you focused on the task at hand and help you work towards comprehension of the entire article.